Kinesin is an ATP-driven molecular motor protein that moves processively along microtubules. Despite considerable research, the detailed mechanism of kinesin motion remains elusive. We applied an ...
A mobile state of the kinesin–ADP head is discovered using multi- and single-molecule fluorescence polarization. The structure of the microtubule–kinesin complex has been determined by cryo-EM. The ...
Researchers used a novel phosphate-activation reagent, 2-MeImIm-Cl, in an improved coupling reaction to increase the yield of ADP- or ATP-containing molecules. Unlike traditional reactions, the ...
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