We have previously described an ovarian cancer model based on four independent spontaneously immortalized epithelial ovarian cancer cell lines (TOV-21G, TOV-81D, TOV-112D and OV-90) from patients who ...

Progress in biology is driven in part by technology, and periodically a new technology enters the scene that radically transforms laboratory investigation. When such landmark technologies first appear ...

NOTE. 260/280 and 260/230 are optical density ratios; CA is the tumor content in percent; % P is the percent of probe sets present; actin and glyceraldehyde-3-phosphate dehydrogenase (GAPDH) are the 3 ...

Yes, many are attracted to next-generation sequencing, but loyalty to chip-based phenotyping has its rewards, particularly in screens of large sample sets. The microarray, the legacy technology for ...

PURPOSE: E-cadherin (E-cad) and its associated intracellular molecules, catenins, are critical for intercellular epithelial adhesion and are often expressed in non–small-cell lung carcinomas (NSCLCs).

For microarrays produced using spotting technologies, much attention has to be given to the development of slide surfaces, attachment chemistries, and spotting solutions. Application of the optimal ...

A survey of scientists developing bioprocesses found efficiency to be the top concern, with pressure growing each year to “produce more, do it more quickly, and do so with fewer resources.” 1 Yet, ...

A recent study highlights how DNA microarray technology enables high-throughput gene analysis, supporting variation detection, expression profiling, and clinical research. By refining probe design and ...