Brain Changes Speak Volumes About Normal Aging and Dementia
Jun 7, 2013 · Brain atrophy plagues more than just people with neurodegenerative disorders. Even seemingly healthy individuals lose brain matter over time. Can doctors and researchers …
Accelerated Brain Volume Loss Caused by Anti-β-Amyloid Drugs: …
Apr 4, 2023 · Clinicians have often associated focal or generalized cerebral atrophy seen on imaging studies with loss of brain tissue, or loss of specific cell types, due to injury or …
Brain Atrophy Patterns Support Distinct Subtypes of ... - ALZFORUM
Aug 3, 2016 · The regions of the brain affected by the disease vary significantly as well. Multiple imaging studies have identified various patterns of atrophy, white-matter damage, and waning …
What About the Brain Shrinkage Seen with Aβ Removal?
Apr 3, 2023 · In general, brain atrophy is considered a marker for neurodegeneration, including in the A/T/N biomarker classification system for Alzheimer’s disease. The Alzheimer’s …
Do Frontoparietal Regions Shrink First in Preclinical Alzheimer’s?
May 2, 2014 · Atrophy heat map: Frontoparietal areas of the brain atrophy faster (red) in people with falling CSF Ab than in those with stable Aβ levels, while temporal regions deteriorate at …
FDA Approves BrainSee, AI Software That Purportedly Predicts AD
Jan 19, 2024 · Years before brain atrophy due to Alzheimer’s disease becomes blatantly obvious on an MRI scan, neurons start to die off in specific regions of the brain. Researchers have long …
Sleep: Too Little, or Too Much, Foreshadows Brain Shrinkage
May 11, 2022 · Too little or too much sleep in middle age tracks with worse cognition. Abnormal sleep also predicts worse cognition and mental health a decade later. And it predicts a smaller …
Is the ‘Atrophy’ of Immunotherapy Just the Dismantling
Aug 28, 2024 · The brain shrinkage seen on amyloid immunotherapy remains an unsolved and concerning riddle. At the Alzheimer’s Association International Conference, held July 27 to …
Trontinemab Fuels Hope for Brain Shuttle Lift-Off | ALZFORUM
May 1, 2025 · According to work by Nick Fox of University College London, so-called “pseudo-atrophy” might be accounted for by removal of plaques along with their “suburban sprawl” of …
Infiltrating CD8+ T cells exacerbate Alzheimer's disease
Sep 1, 2023 · Inhibition of IFNγ significantly ameliorated brain atrophy (Chen et al., 2023). It is interesting to investigate if blocking IFNγ receptors in specific cells, including microglia, would …