Heterocyclic chemistry is a branch of chemistry that deals with compound s, products, reactions, and applications.2 Aminoguanidine bicarbonate has attracted recent attent ion due to its practical …

The latter enzyme has been the target of the antifolates 5-deazacy-clotetrahydrofolate [18] and N-[4-[2-2(amino-3,4-dihydro-4-oxo-7H-pyrrolo [2,3-d]pyrimidin-5-yl)ethyl]-benzoyl]-L-glutamic acid, each of …

6 days ago · Johannes H. Harenberg et al. reviewed advances in the application of flow chemistry to organolithium reactions, covering the generation of organolithium reagents, the preparation of …

I. PARMAR*, H. RATHOD1 AND S. SIDDIQUE1 Department of Pharmaceutical Chemistry, 1Department of Quality Assurance, S.S.R. College of Pharmacy, S.S.R. Campus, Sayli Road, …

Table 1 List of FDA-approved kinase inhibitors with fused heterocyclic rings Name Structure Target Fused heterocycle References Abemaciclib CDK4/6 benzimidazole [157] Acalabrutinib Bruton …

it is difficult to prepare the compound of Formula ( I ) having methyl ) -3 - phenyl - 1H - pyrazol - 1 - yl ) pyrimidin - 2 - yl ) -6 a suitable purity . methoxy - 4 - morpholinobenzene - 1,3 - diamine ( the …

However, it is noteworthy that the lives of 60 h and 25 h, respectively. Both compounds were inversion of the methyl position dramatically in uences the Pd – found to be thermally sensitive and degraded …